Research Team Discovers New Immune “Checkpoint” Protein

immunotherapy

A recent report in the journal Cell showed that a team led by Vanderbilt researchers has found a new “checkpoint” protein on immune system cells in active, malignant tumors. In mouse models, blocking this protein, along with using other treatments, has been an effective approach to treating cancerous cells. Checkpoint proteins are an important component of […]

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How Charlotte Trainer Beat Stage-4 Cancer at CHIPSA Hospital!

Charlotte Trainer Cancer CHIPSA

How Charlotte Trainer Beat Stage 4 Cancer at CHIPSA Hospital Charlotte Trainer thought she was out of options when she was diagnosed with Stage-4 inoperable Endometrial cancer in November of 2017. After having a full hysterectomy and 25 rounds of radiation, her doctors told her that the cancer had metastasized to her lungs. There was […]

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Study Shows Better Immunotherapy Outcomes in Tumors with More Mutations

Immunotherapy

A recent study published in Nature Genetics called “Tumor mutational load predicts survival after immunotherapy across multiple cancer types” revealed that tumors with more mutations had better results with immunotherapy treatment. The study looked at data from 1,662 metastatic cancer patients who received checkpoint inhibitor therapy, and data from over 5,000 patients who were not treated […]

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Researchers Use AI to Improve Immunotherapy Outcomes

immunotherapy

A research team from the University of Maryland is utilizing artificial intelligence (AI) to determine the most effective ways to treat cancer patients with immunotherapy. Immunotherapy takes advantage of the body’s own immune system to fight off cancer, and in the past decade, it has been very successful in treating patients with localized and advanced […]

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Phase 3 Trial Tests Tyvyt as Esophageal Cancer Therapy

esophageal cancer

The ORIENT-15 Phase 3 clinical trial evaluating Tyvyt (sintilimab injection) combined with chemotherapies Taxol (paclitaxel) and Platinol (cisplatin) as treatment for esophageal squamous cell carcinoma is now underway. Tyvyt was developed by Innovent Biologics and Eli Lilly and Company in China as an immune checkpoint inhibitor that will work against PD-1, a protein found on […]

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Tecentriq Triple Combo Under FDA Review for NSCLC Treatment

NSCLC

Genetech has announced that the U.S. Food and Drug Administration (FDA) will be reviewing its Tecentriq (atezolizumab) combined with chemotherapy drugs Abraxane (nab-paclitaxel) and carboplatin for treatment of metastatic non-squamous non-small cell lung cancer (NSCLC). The drug will be for patients without any mutations in the EGFR and ALK genes.   Tecentriq is a checkpoint inhibitor drug that targets […]

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Scientists Discover New Way to Predict Immunotherapy Responses

coley's CPG

Immune checkpoint inhibitors like Keytruda offer new ways to treat cancer patients who might otherwise have no options. But the treatment has posed challenges to health care professionals when it comes to figuring out which tumors will respond to immunotherapy and which tumors won’t. A research team at Memorial Sloan Kettering Cancer Center in New […]

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New Video Series Celebrates 22 Late-Stage Cancer Survivors

Last September, 22 people made history as they joined together to celebrate accomplishing the impossible: surviving late-stage cancer. Traveling back to the place where their healing journeys began — CHIPSA Hospital in Tijuana, Mexico — the cancer survivors had the chance to share their stories, meet other patients, and converse with world-renowned doctors, scientists, coaches, and […]

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