Charlotte T. Beats Stage-4 Cancer with Cryoablation and Combination Therapy at CHIPSA Hospital!

Charlotte Trainer thought she was out of options when she was diagnosed with Stage-4 inoperable Endometrial cancer in November of 2017. After having a full hysterectomy and 25 rounds of radiation, her doctors told her that the cancer had metastasized to her lungs. There was nothing else they could offer her except high dose chemo to extend her life up to 12 months.

Today she celebrates being cancer free 4.5 years after being treated at CHIPSA hospital.

How did Charlotte go from Stage 4 Cancer to a clear PET scan?

She and her husband wouldn’t accept that there was nothing else to be done. After doing some research, they figured out that CHIPSA could offer Charlotte other options for healing.

It wasn’t an easy decision for the Trainers to head all the way to Mexico for treatments, especially when their family members, friends, and doctors were urging them not to. They even had to miss out on a Thanksgiving at home. “When I told friends that I was going to be trying the procedures and therapies at CHIPSA,” said Charlotte, “they thought I should be afraid of going to Mexico. You hear all that, and you start to wonder if there’s any hope. But we came anyway.

After discovering that Charlotte’s cancer had spread to her liver and lung, her doctor told her that chemotherapy only had about a 30% chance of efficacy in treating her cancer. That left her with little hope.

But the second she walked through CHIPSA’s doors, her outlook changed:

The very first day I walked into CHIPSA,” said Charlotte, “there was so much love and hope here that you just couldn’t not get well. You couldn’t not be hopeful. I was there for three weeks. We decided we were just going to throw the book at it all. All the therapies they suggested, we were going to try.” 

According to Dr. Omar Pizano, one of CHIPSA’s attending physicians, Charlotte received many of its protocols, including cryoablation, Vitamin CK3 (Apatone) therapy, Coley’s Therapy, and the Gerson Therapy. She completely changed her diet, began a juicing regimen, and cleansed her body with coffee enemas. But Charlotte did not receive alternative therapies alone. She also got a Opdivo with her cryoablation therapy.

That’s what is so unique about CHIPSA. Their treatments aren’t just alternative, they are integrative. As Dr. Pizano says, “We use the best of both worlds — the best of conventional medicine and the best of alternative medicine. Everything works synergistically for the greater good of the patient.”

After spending three weeks at CHIPSA, Charlotte and her husband went home to Nashville and continued her regimen there. Her family supported her to stay on track with her diet and coffee enemas, and they even hired a woman to come in and make fresh juices for her.

“And now I’ve gotten the diagnosis of CLEARED,” Charlotte said. “Because the PET scan had nothing reflected on it at all. When I got that second PET scan as being clear, I had no words. I was blown away. It was certainly worth all the work.”

What was the key to Charlotte’s success?

ryan and charlotteCHIPSA provided her with the treatments and tools she needed to help her body heal. But Charlotte’s hard work at home likely also contributed greatly to her outcome, says Dr. Pizano. “For a patient’s success, they need to stick with what the doctors prescribe and try to follow it as much as they can,” he said. “The minimum we expect the patient to keep doing the treatments is at least 18 months. We want them to see it not as a treatment, but as a lifestyle that will help them stay in remission for the rest of their lives.”

Charlotte is certainly doing all she can to preserve the healing that she believes CHIPSA helped her achieve: “I don’t want to take any chances with not doing the juicing that I need to do, and eating properly, and the cleanses that are a part of the program. But I’m healthy now, and that’s the way it’s going to stay.” 

The family members who urged Charlotte not to go to CHIPSA are now thankful that she did. And Charlotte herself says she can’t imagine having gone anywhere else:

“I feel like family when I walk in the door. It’s a wonderful feeling. I can’t recommend it enough to people. This is the place that has given me hope and new life. From here on out, every day is a gift. Thank you CHIPSA.” 

Charlotte’s Integrated Protocol Included…


Cryoablation for cancer is a minimally‐invasive treatment to kill cancer cells with extreme cold to actually freeze a tumor to death.

During cryoablation, a thin cryoprobe, wandlike needle is guided through the skin and directly into the cancerous tumor. Liquid nitrogen gas is pumped into the cryoprobe in order to freeze the tissue. Then the tissue is allowed to thaw. The freezing and thawing process is repeated several times during the same treatment session.

Cryoablation when combined with direct intramural injections of immunotherapy creates a vaccine effect inside the patients body often causing the abscopal effect.

The abscopal effect is where shrinkage of untreated tumors occurs concurrently with shrinkage of tumors within the scope of the localized treatment.

Coley’s Toxins

Coley’s Mixed Bacterial Vaccine (Mixed Bacterial Vaccine), also known as Coley’s Toxins or Coley Fluid (CF) is a treatment originally developed in 1891 by Memorial Hospital surgeon, Dr. William Coley.


How It Works:

Coley’s Mixed Vaccine is comprised of a sterile(dead) mixture of gram-positive Streptococcus pyogenes and gram-negative Serratia marcescens bacteria. By introducing the killed bacteria into the body, Dr. Coley could mimic an immune response without the risk of infection.

Since cancer cells were formed undetected, the goal is to “unlock” the body’s immune system so that it can identify and kill cancer cells.

Dosage: Graduated dosing averages 2x weekly.  It invokes a very strong immune reaction that includes flu-like symptoms, fever, aches, and chills. It builds up the immune system and cancer fighting dendritic cells are unleashed to go present tumor antigens to the T-Cell.

  • Coley’s toxins are generally administered 2-3 times per week at a dose which achieves a body temperature of between 39.5 °C to 41 °C (approximately 103 °C to 106 °F), while being monitored by qualified medical staff.
  • The exact number of treatments per week may vary depending on each individual patient and other circumstances.
  • About 5-6 hours of treatment are required for each treatment day.
  • Vital signs (blood pressure, heart rate, respiratory rate, temperature) are constantly monitored by professional and experienced medical staff.
  • Coley’s toxins have a very long and safe history of use.
  • Generally patients experience improved well being after each treatment.
  • This treatment is ideally used in conjunction with other immunotherapies, such as Gerson Therapy, personalized Dendritic Cell Vaccine, and Tumor Lysate Vaccine

Note: CHIPSA is the only licensed hospital facility treating with the Coley’s  Toxins in North America.



Vitamin CK3 (Apatone)

Apatone is the combination Vitamin C and Vitamin K3 in a specific ratio of 100:1.

It was discovered by Dr. Henryk Taper of the University of Leuven in Brussels, Belgium, who noted that moderate doses of Apatone  were assisting in the elimination of various cancer cells

The way that many of the anti tumor drugs work, is by targeting dividing cells or by going after the blood vessels of the tumor. Apatone on the other hand target the anti inflammatory response of the cancer cell.

Normal human cells utilize sugars and fats for metabolism, whereas cancer cells prefer glucose. And that is where the weakness lies.

The structure of Apatone resembles glucose and thus the Apatone is able to enter the the cancer cell via the glucose transport system where it causes oxidation via quinone. This has been shown in studies to cause a unique immunogenic cell death.

The Apatone Clinical Trial

In 2004, a California biotech company IC-MedTech, purchased the rights to Apatone. The first human clinical trial began in 2005 with 17 end-stage prostate cancer patients. The clinical trials, which were conducted at Summa Health System in Akron, Ohio were monitored for 12 weeks. Apatone was administered orally each day.

Throughout the trial, investigators noted the PSA levels, PSA velocity and PSA doubling rates.

  • PSA is a protein produced by the prostate gland. Prostate cancer patients exhibit increased levels of this protein
  • PSA velocity is the change of PSA levels during a period
  • PSA doubling time is the time it takes for a PSA levels to double.

16 of the 17 patients responded well to the Apatone and 13 showed a decrease in PSA velocity and an increase in PSA doubling time. The Apatone appeared to be killing cancer.

Showing progress in the biochemical progression of late stage prostate cancer patients, the trial was able to show safety and even a signal of efficacy.

No More Apatone in The United States

Unfortunately this is where things came to an end in the United States. Even though the results of this non toxic cancer treatment were favorable, the exceeding costs of continuing the FDA process became too much for IC-MedTech.. The cost of bringing a treatment to market can exceed 1 billion dollars.

Apatone At CHIPSA

In 2016 Chipsa Hospital partnered with IC-Med Tech and Apatone has been a part of the protocol for most cancer patients. Since then CHIPSA has treated over 1,000 patients with Apatone. It has been successfully combined with low doses of chemotherapy, checkpoint inhibitors and other immunotherapy treatments.

Gerson Therapy Immuno-Nutrition

Initially Developed by Dr. Max Gerson in the 1920’s for the treatment of tuberculosis and headaches, Gerson Therapy was applied towards cancer patients in 1928. It is a specific diet-based immunological detoxification and nutrition protocol that is the foundation of the treatments here at CHIPSA.

Gerson therapy focuses on reactivating your body to heal itself through non toxic methods including organic foods, juicing, detoxification and supplements.


Dr. Max Gerson

The diet includes raw and cooked foods in its three daily vegan meals.

Additionally, patients can expect anywhere from 10-12 fresh and raw organic juices per day. These are  prepared with specific organic fruits and vegetables. These fruits and vegetable are harvested for their enormous quantities of phytochemicals. These phytochemicals are currently being studied worldwide for their exciting anticancer and health promoting properties. The vast amount of nutrients “super charge” the patient’s immune system.

Oncological diet therapy is a medical specialty, not unlike oncological radiotherapy. In some instances, diet therapy will be sufficient to cause complete regression of cancer. CHIPSA clinical scientists believe that complementary use of medical specialties will lead to more satisfactory overall outcomes when complementary medical protocols are co-implemented.


Opdivo (nivolumab) is a monoconal antibody that doctors may prescribe to patients with qualifying cancers. It is a “systemic” type of immunotherapy that travels throughout the blood stream. Opdivo aims to help shrink tumors and reduce the risk of cancer coming back after surgery.

As a checkpoint inhibitor, the way that Opdivo works is by blocking the activity of a protein called PD-1. PD-1 prevents your immune system from recognizing and attacking cancer cells.

This treatment was injected directly into the tumor during they cryoablation procedure.

The Future of Cancer Treatment?

Charlotte’s protocol is just one of the many ways that CHIPSA Hospital aims to bring integrative health care to forefront of cancer treatment. Stage 4 cancer is a very complicated disease and there is no easy answer for it.

The medical practice at CHIPSA Hospital has been treating patients through integrative medical protocols since 1979 . This now includes cutting edge immunotherapies like checkpoint inhibitors and innate immune stimulating treatments. We are  also using lower doses of conventional oncological medications to cause damage to cancer cells, while at the same time stimulating the innate immune system to recognize the danger signals and attack the cancer cells.


CHIPSA uses the best of both worlds. The best of conventional medicine and the best of alternative medicine…. everything works synergistically for the greater good of the patient. – Dr Omar Pizano

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