Archive

Category Archives for "immunotherapy"

First Patient Receives Phase 1 Clinical Trial Dose of FS118

clinical trial

  The clinical trial for an antibody designed to treat advanced cancers has begun with the first dose of FS118. The treatment is supposed to target two immune checkpoint proteins. The study, based in the US, will be enrolling 51 patients who have been diagnosed with metastatic cancers. The patients have not previously responded to […]

Continue reading

What is Immuno-Oncology?

immunotherapy

  The immune system is a collection of molecules in every living thing that protects its cells. It relies on the ability to tell the difference between its own body cells and foreign cells, called antigens, in order to protect the body from the harmful antigens. The immune system has a set of proteins commonly […]

Continue reading

T-Cell “ImmunoMap” Could Increase Response Predictability

t-cell

Johns Hopkins’ scientists have crafted a digital map, also called “ImmunoMap”, although still undergoing development, that can someday be used to identify which cancer patients will respond successfully to immunotherapies. This digital map addresses the variability of T-cell receptors which are chemical antennas that identify antigens and trigger an immune response. Through this digital map, […]

Continue reading

NK Cell Function Identified in Mice

NK cell

A new checkpoint protein that hampers natural killer (NK) cell-mediated tumor immunity was recently discovered by Australian researchers. Results from the study shows that depleting this protein in mice makes them resistant to a lot of solid cancers by turning on NK cell activity. This study, “CIS is a potent checkpoint in NK cell mediated […]

Continue reading