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JAK Mutations a Possible Indicator of Drug Resistance

JAK mutations

JAK Mutations are genetic abnormalities that affect the production of red blood cells. They are often found in individuals with polycythemia vera, as well as a number of other myeloproliferative neoplasms. The anti-PD-1 agent, Keytruda (pembrolizumab) was approved in 2014 by the U.S. Food and Drug Administration for the treatment of advanced melanoma. Since then, it has received […]

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