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JAK Mutations a Possible Indicator of Drug Resistance

JAK mutations

JAK Mutations are genetic abnormalities that affect the production of red blood cells. They are often found in individuals with¬†polycythemia vera, as well as a number of other¬†myeloproliferative neoplasms. The anti-PD-1 agent, Keytruda (pembrolizumab) was approved in 2014 by the U.S. Food and Drug Administration for the treatment of¬†advanced melanoma. Since then, it has received […]

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